Анотация: With regard to the most convenient laboratory diagnostics of C. perfringens infections and those caused by some weakly haemolytic bacteria, attempt to determine their relationships in the CAMP test in different combinations were carried out. For this purpose, agar supplemented with 10 percentage defibrinated sheep blood was used as nutrient medium. The incubation was carried out in aerobic, microaerophilic and anaerobic conditions. C. perfringens type А showed a clear САМР test reaction with S. agalactiae and R. equi, but not with S. aureus, whereas R. equi exhibited a positive reaction with S. aureus and vice versa (S. Aureus showed a positive reaction with R. equi, when the latter was used as haemolysis-enhancing factor). The attempts to use C. perfringens as haemolysis-enhancing factor showed that it exhibited a positive САМР test result with R. equi, but there was no reaction with S. aureus. When used as a haemolysisenhancing factor with regard to L. monocytogenes type 1/2 а, 4b and L. ivanovi, C. perfringens showed al almost equal reaction with a slightly stronger haemolysis with L. ivanovi. This reaction became more detectable when the incubation time was prolonged up to 48 h