Анотация: CXC chemokine receptors 1 (CXCR1) play a key role in inflammatory response and eventual activation of the innate immunity. Mastitis is a big problem in dairy industry. In the presented study the bovine CXCR1 gene was considered a candidate gene of anti-mastitis defense in Chinese Holsteins. Polymorphism of bovine CXCR1 was investigated and its associations with Somatic Cell Scores (SCS) and milk production traits (milk yield, milk fat and milk protein content) analysed