Анотация: Hemochromatosis in bottlenose dolphins (Tursiops truncatus) is associated with high postprandial plasma insulin levels, suggestive of insulin resistance. In humans, insulin resistance is associated with liver pathologies, including excessive iron deposition and nonalcoholic fatty liver disease. Dolphin liver tissues, in addition to excessive iron storage, were evaluated for other pathologies supportive of underlying insulin resistance. Archived liver tissues collected postmortem during 1985-2010 from 18 dolphins (median age 27.9 yr, range 0.7-51.4) that were part of the Navy Marine Mammal Program`s managed collection were assessed for the presence and severity of hemosiderin deposition, fatty liver disease, and hepatitis. Demographics, clinical pathology values, and percentage weight loss were compared among dolphins with and without these changes