Description: Objective: The surgical treatment of cerebral metastases is an everyday problem in neurosurgical practice. The subject of treatment is mostly single metastases of the brain. To minimize therapeutic morbidities, such as cortical injuries, a transsulcal approach was applied by taking the results of neuroimaging into consideration. We aimed at introducing in the everyday clinical practices this approach to the surgical treatment of this pathology. Methods: We present 61 cases of intra-cerebral metastases treated surgically by trans-sulcal microsurgical approach at the Neurosurgical Clinic of Stara Zagora University Hospital. 39 of them are men and 22 are women, aged 42 to 69. According to the outcome of CT and MRI, the chosen sulcus was opened toward the lesion. Following complete dissection of the sulcus to remove the lesion. Results: The trans-sulcal microsurgical access was successfully conducted. In the early postsurgical period, all patients experienced a regress of the neurological deficit and improvement of the overall condition. Conclusion: The trans-sulcal microsurgical approach ensures less traumatic surgical interventions and preserves as much as possible the physiological and anatomical structures of the cerebrum