Description: The present study was performed on 132 clinically healthy Iranian native goats from both sexes (36 male and 96 female). The blood concentrations of malondialdehyde (MDA), superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPX) were determined. The reference values for oxidative stress parameters of adult clinically healthy Iranian native goats were as followed: SOD 778.65-1190.50 U/g Hb, GPX 266.67-322.00 U/g Hb, CAT 1536.29-2215.63 U/g Hb and MDA 0.346-0.801 mmol/l. There were no significant differences in oxidative stress parameters between the two sexes