Description: Studies for detection of antibodies against an isolate of influenza A virus H6N2 were carried out by ID, ELISA and HI with 38 experimental turkey poults, 9 of which were infected intravenously, 9 tracheally, 8 orally, 6 by contact and 6 control. Titre, antibody and S/P values by ELISA differed from test to test and route of infection. ID detected 100 percentage positive poults after intravenous, 85.71 percentage after tracheal, 83.33 percentage after oral infection and 66.67 percentage positive contact poults. Lower values were obtained with ELISA in the orally infected poults (80 percentage) and with Нт in the contact poults (50 percentage). The highest per cent HI positive results were obtained on the 14th day and on the 21st day with ID and ELISA.. - HI detected more positive sera than ID and ELISA in the intravenously and tracheally infected groups. ID detected more positive contact birds than HI and ELISA. The highest precipitin titres varied in relation to the route of infection starting with the tracheal, oral, intravenous and spontaneous (contact) infection. The S/P of ELISA and the haemagglutinin titre reached high values after intravenous infection and lower values after tracheal, spontaneous and oral infection. Highest sensibility to infection in turkey poults showed HI followed by ID (93.75 percentage - 72 percentage) and ELISA (89.66 percentage - 68 percentage). In the contact poults ID detected more positive birds than ELISA (88.89 percentage) and HI (77.77 percentage). ELISA and ID results varied from 86.67 percentage - 88.,89 percentage