Description: Ten (10) lambs, aged four (4) months, were used for the study. They were taken from each of the following breeds: Native Karnobat, Karakachan and Rodopa Sheep. Biopsy samples of skins were taken from the flank of these animals. The total thickness of skin and its layers, depth and width of hair bulbs, width of primary and secondary fibre roots and sizes of skin glands were obtained. The lambs of Karakachan Breed had the biggest total skin thickness and layer thickness (3309,2 m) while the lambs of Native Karnobat Breed had the smallest (2531 m). Measurements from the Rhodopa Sheep were in the median position. Lambs of the Rhodopa sheep had skin structure in which the primary and secondary follicles were sequestered deeply in the dermis while these follicles were not so deep in skins from the Native Karnobat Breed lambs. Lambs of the Karakachan breed had the largest-sized fat and sweat glands