Description: Comparative studies were carried out to evaluate the non-specific resistance and some metabolic profile parameters in Mouton Charollais sheep (n=16) and their offspring (n=10) depending on diet type. It was found out that the compound feed type had various effects on studied parameters. Blood lipids and T increased statistically significantly (p<0.05) in sheep. In offspring, considerable changes were observed in blood urea, APCA (p<0.05), body weight and 3 daily weight gain (p<0.01). There were no significant changes in the other parameters tested (lysozyme, total protein, г-GT and T4 )